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Fructosamine-3-kinase-related Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-56367

Novus Biologicals, part of Bio-Techne
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NBP1-56367

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Synthetic peptides corresponding to FN3KRP(fructosamine-3-kinase-related protein) The peptide sequence was selected from the N terminal of FN3KRP. Peptide sequence MDPGDPAGDPAAGERHRMGRDPLLLLQALQTLWSTRERKQLREEAWRGFA. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Fructosamine-3-kinase-related Antibody

Western Blot: Fructosamine-3-kinase-related Antibody [NBP1-56367]

Western Blot: Fructosamine-3-kinase-related Antibody [NBP1-56367]

Western Blot: Fructosamine-3-kinase-related Antibody [NBP1-56367] - Jurkat cell lysate, concentration 0.2-1 ug/ml.

Applications for Fructosamine-3-kinase-related Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Fructosamine-3-kinase-related

FN3KRP phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein-bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation.FN3KRP and FN3K (MIM 608425) protect proteins from nonenzymatic glycation by phosphorylating the modified amino acid. This phosphorylation destabilizes the sugar-amine linkage and leads to spontaneous decomposition (Conner et al., 2004 [PubMed 15381090]).[supplied by OMIM].

Alternate Names

EC 2.7.1.-, EC 2.7.1.172, FLJ12171, FN3KL, FN3K-related protein, FN3KRP, FN3K-RP, fructosamine 3 kinase related protein, Fructosamine-3-kinase-related protein, ketosamine-3-kinase, Protein-psicosamine 3-kinase FN3KRP

Gene Symbol

FN3KRP

UniProt

Additional Fructosamine-3-kinase-related Products

Product Documents for Fructosamine-3-kinase-related Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Fructosamine-3-kinase-related Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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