gamma-Glutamylcyclotransferase/CRF21/GGCT Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86728

Novus Biologicals, part of Bio-Techne
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NBP1-86728
NBP1-86728-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all gamma-Glutamylcyclotransferase/CRF21 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QEGVKSGMYVVIEVKVATQEGKEITCRSYLMTNYESAPPSPQYKKIICMGAKENGLPLEYQEKLKAIEPNDYTGKVSEEIE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (84%). Reactivity reported in scientific literature (PMID: 22205682)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for gamma-Glutamylcyclotransferase/CRF21/GGCT Antibody

Western Blot: gamma-Glutamylcyclotransferase/CRF21/GGCT Antibody [NBP1-86728]

Western Blot: gamma-Glutamylcyclotransferase/CRF21/GGCT Antibody [NBP1-86728]

Western Blot: gamma-Glutamylcyclotransferase/CRF21/GGCT Antibody [NBP1-86728] - Analysis in human cell line A-431 and human cell line A-549.
Immunohistochemistry-Paraffin: gamma-Glutamylcyclotransferase/CRF21/GGCT Antibody [NBP1-86728]

Immunohistochemistry-Paraffin: gamma-Glutamylcyclotransferase/CRF21/GGCT Antibody [NBP1-86728]

Immunohistochemistry-Paraffin: gamma-Glutamylcyclotransferase/CRF21/GGCT Antibody [NBP1-86728] - Staining of human small intestine shows strong cytoplasmic positivity in glandular cells.

Applications for gamma-Glutamylcyclotransferase/CRF21/GGCT Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: gamma-Glutamylcyclotransferase/CRF21

CRF21 (Cytochrome c-releasing factor 21; also C7orf24 or LOC79017) is a 21 kDa AIG2-like family member. It is a cytosolic protein that induces the release of Cytochrome c from mitochondria, possibly initiating apoptosis. Human CRF21 is 188 amino acids (aa) in length and is a complex of beta-sheets and alpha-helices that create two terminal domains. It has been proposed that CRF21 forms homodimers. There are at least two possible splice variants of human CRF21, one showing a 70 aa substitution, while the second variant shows an 18 aa substitution for aa 97-188. Full-length human CRF21 is 82% aa identical to mouse CRF21.

Long Name

Cytochrome c Releasing Factor 21

Alternate Names

C7orf24, CRF21, gammaGlutamylcyclotransferase, GCTG, GGC, GGCT, LOC79017

Gene Symbol

GGCT

Additional gamma-Glutamylcyclotransferase/CRF21 Products

Product Documents for gamma-Glutamylcyclotransferase/CRF21/GGCT Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for gamma-Glutamylcyclotransferase/CRF21/GGCT Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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