HIST1H2BC Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-31878

Novus Biologicals, part of Bio-Techne
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NBP2-31878
NBP2-31878-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HIST1H2BC Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: PDPSKSAPAPKKGSKKAVTKAQKKD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HIST1H2BC Antibody

Immunocytochemistry/ Immunofluorescence: HIST1H2BC Antibody [NBP2-31878]

Immunocytochemistry/ Immunofluorescence: HIST1H2BC Antibody [NBP2-31878]

Immunocytochemistry/Immunofluorescence: HIST3H2BB Antibody [NBP2-31878] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
Immunohistochemistry: HIST1H2BC Antibody [NBP2-31878]

Immunohistochemistry: HIST1H2BC Antibody [NBP2-31878]

Immunohistochemistry: HIST3H2BB Antibody [NBP2-31878] - Staining of human kidney shows moderate nuclear positivity in cells in tubules.

Applications for HIST1H2BC Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HIST1H2BC

HIST1H2BC is 126 amino acids long, weighs approximately 14 kDa, and the gene codes for a part of a group of basic nuclear proteins called histones, which are responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Current studies are being done on several diseases and disorders including systemic lupus erythematosus, lupus erythematosus, hemochromatosis, and immunodeficiency. HIST1H2BC has also been shown to have interactions with HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, and HIST1H4E in pathways such as the histone modification, signal transduction of Activin A, telomere maintenance, nucleosome assembly, cell cycle, and systemic lupus erythematosus pathways.

Alternate Names

H2B histone family, member K, H2B/a, H2B/g, H2B/kH2B/h, H2BFA, H2BFG, H2BFH, H2BFKH2B/l, H2BFL, HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, histone 1, H2bi, histone cluster 1, H2bi, histone H2B type 1-C/E/F/G/I, Histone H2B.1 A, Histone H2B.a, Histone H2B.g, Histone H2B.h, Histone H2B.k, Histone H2B.l

Gene Symbol

HIST1H2BC

Additional HIST1H2BC Products

Product Documents for HIST1H2BC Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for HIST1H2BC Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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