TWEAK/TNFSF12 293T Cell Transient Overexpression Lysate, Novus Biologicals

Name: TWEAK/TNFSF12 293T Cell Transient Overexpression Lysate
Brand: Novus Biologicals
SKU: H00008742-T01

Bio-Techne includes Novus Biologicals | Catalog # H00008742-T01

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Product Summary
Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species

Human

Applications

Western Blot

Product Summary for TWEAK/TNFSF12 293T Cell Transient Overexpression Lysate

Quality control test: Transient overexpression cell lysate was tested with Anti-TNFSF12 antibody by Western Blots. Plasmid: pCMV-TNFSF12 full-length

Product Specifications

Specificity

TWEAK/TNFSF12 293T Cell Transient Overexpression Lysate(Denatured)

Type

293T Cell Transient Overexpression

Protein State

Denatured

Scientific Data Images for TWEAK/TNFSF12 293T Cell Transient Overexpression Lysate

Lane 1: TNFSF12 transfected lysate (14.85 KDa) Lane 2: Non-transfected lysate.

TNFSF12 transfected lysate.

Formulation, Preparation, and Storage

Formulation

1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)

Concentration

mg/ml

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -80C. Avoid freeze-thaw cycles.

Background: TWEAK/TNFSF12

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Some transcripts that skip the last exon of this gene and continue with the second exon of the neighboring TNFSF13 gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq]

Long Name

TNF-like and Weak Inducer of Apoptosis

Alternate Names

TNFSF12

Gene Symbol