CLCN7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-91791

Novus Biologicals, part of Bio-Techne
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NBP1-91791
NBP1-91791-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CLCN7 Antibodies »

Product Summary for CLCN7 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LYDMHIQLQSVPFLHWEAPVTSHSLTAREVMSTPVTCLRRREKVGVIVDVLSDTASNHNGFPVVEHADDTQPARLQGLILRSQLIVLLKHKVFVERS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CLCN7 Antibody

Immunocytochemistry/ Immunofluorescence: CLCN7 Antibody [NBP1-91791]

Immunocytochemistry/ Immunofluorescence: CLCN7 Antibody [NBP1-91791]

Immunocytochemistry/Immunofluorescence: CLCN7 Antibody [NBP1-91791] - Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: CLCN7 Antibody [NBP1-91791]

Immunohistochemistry-Paraffin: CLCN7 Antibody [NBP1-91791]

Immunohistochemistry-Paraffin: CLCN7 Antibody [NBP1-91791] - Staining of human duodenum shows strong granular cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: CLCN7 Antibody [NBP1-91791]

Immunohistochemistry-Paraffin: CLCN7 Antibody [NBP1-91791]

Immunohistochemistry-Paraffin: CLCN7 Antibody [NBP1-91791] - Staining of human testis shows moderate granular cytoplasmic positivity in cells in seminiferous ducts.
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Applications for CLCN7 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CLCN7

The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.

Alternate Names

chloride channel 7, Chloride channel protein 7, CLC-7, CLC7FLJ39644, FLJ26686, H(+)/Cl(-) exchange transporter 7, OPTA2FLJ46423, OPTB4

Gene Symbol

CLCN7

Additional CLCN7 Products

Product Documents for CLCN7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CLCN7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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