STAT5a/b [p Tyr694, p Tyr699] Antibody (1247C) [Alexa Fluor® 488]
Novus Biologicals, part of Bio-Techne | Catalog # FAB41901G
Key Product Details
Species Reactivity
Validated:
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Product Summary for STAT5a/b [p Tyr694, p Tyr699] Antibody (1247C) [Alexa Fluor® 488]
Immunogen
Accession # P51692
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Applications for STAT5a/b [p Tyr694, p Tyr699] Antibody (1247C) [Alexa Fluor® 488]
CyTOF-ready
Intracellular Staining by Flow Cytometry
Western Blot
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Background: STAT5a/b
Signal transduction and activator of transcription 5 (STAT5) is a member of the Jak/STAT signal transduction pathway and is activated by a variety of cytokines (IL22, IL6, IFN-α). STAT5 has two isoforms (A and B) that share 93% amino acid identity and bind the DNA consensus site TTCN3GAA. STAT5 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, translocates to the nucleus and activates transcription of specific genes. STAT5 is involved in a wide array of biological processes ranging from regulating apoptosis to adult mammary gland proliferation, differentiation and survival.
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Additional STAT5a/b Products
Product Documents for STAT5a/b [p Tyr694, p Tyr699] Antibody (1247C) [Alexa Fluor® 488]
Product Specific Notices for STAT5a/b [p Tyr694, p Tyr699] Antibody (1247C) [Alexa Fluor® 488]
Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.