MXRA8/DICAM: Proteins and Enzymes
DICAM, also known as Limitrin and MXRA8, is a transmembrane adhesion protein that is expressed on the endothelium of many tissues. In the vascular system, it is found on pericytes, vascular endothelial cells (EC), and the vessel-contacting feet of astrocytes. It is upregulated on EC by VEGF and functions as a negative regulator of angiogenesis. It inhibits VEGF-induced signaling, cell migration, capillary tube formation, and in vivo angiogenesis, and promotes EC apoptosis. The interaction of DICAM with Integrin alpha V beta 3 enhances cell adhesion and inhibits the differentiation of osteoclasts.
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2 results for "MXRA8/DICAM Proteins and Enzymes" in Products
2 results for "MXRA8/DICAM Proteins and Enzymes" in Products
MXRA8/DICAM: Proteins and Enzymes
DICAM, also known as Limitrin and MXRA8, is a transmembrane adhesion protein that is expressed on the endothelium of many tissues. In the vascular system, it is found on pericytes, vascular endothelial cells (EC), and the vessel-contacting feet of astrocytes. It is upregulated on EC by VEGF and functions as a negative regulator of angiogenesis. It inhibits VEGF-induced signaling, cell migration, capillary tube formation, and in vivo angiogenesis, and promotes EC apoptosis. The interaction of DICAM with Integrin alpha V beta 3 enhances cell adhesion and inhibits the differentiation of osteoclasts.
Products:
| Source: | CHO |
| Accession #: | Q9BRK3 |
| Applications: | BA |
| Applications: | AC |