(+)-Clopidogrel hydrogen sulfate

Name: (+)-Clopidogrel hydrogen sulfate
Brand: Tocris Bioscience
SKU: 1820

Tocris Bioscience, part of Bio-Techne | Catalog # 1820

Citations (7)

COA / SDS

Selective P2Y12 antagonist

Key Product Details

Chemical Name:	(S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogen sulfate
Purity:	≥99%
Molecular Weight:	419.9 kDa

View Full Technical Details for (+)-Clopidogrel hydrogen sulfate

Technical Data
Citations

Biological Activity for (+)-Clopidogrel hydrogen sulfate

(+)-Clopidogrel hydrogen sulfate is a selective, high affinity P2Y₁₂ receptor antagonist. Inhibits ADP-induced platelet aggregation and displays antithrombotic activity. Active enantiomer of (±)-clopidogrel hydrochloride (Cat. No. 2490). Requires bioactivation.

Technical Data for (+)-Clopidogrel hydrogen sulfate

M. Wt	419.9 kDa
Formula	C₁₆H₁₆ClNO₂S.H₂SO₄
Storage	Store at RT
Purity	≥99%
CAS Number	120202-66-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for (+)-Clopidogrel hydrogen sulfate

Solubility

Soluble Soluble to 100 mM in water and to 100 mM in DMSO

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References for (+)-Clopidogrel hydrogen sulfate

References are publications that support the biological activity of the product.

AS Clarke, E Rousseau, K Wang, JY Kim, BP Murray, R Bannister, F Matzkies, KS Currie, JA Di Paolo Effects of GS-9876, a novel spleen tyrosine kinase inhibitor, on platelet function and systemic hemostasis Thromb. Res., 2018;170(0):109-118. 2018 PMID: 30172129
Kugelgen Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol.Ther., 2006;110:415 PMID: 16257449
Savi and Herbert Clopidogrel and ticlopidine: P2Y₁₂ adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin.Thromb.Haemostas., 2005;31:174
Reist et al. Very low chiral inversion of clopid. in rats: a pharmacokinetic and mechanistic investigation. Drug Metab.Disp., 2000;28:1405
Savi et al. P2Y12, a new platelet ADP receptor, target of clopid. Biochem.Biophys.Res.Comm., 2001;283:379