(RS)-(Tetrazol-5-yl)glycine

Name: ( RS )-(Tetrazol-5-yl)glycine
Brand: Tocris Bioscience
SKU: 0312

Tocris Bioscience, part of Bio-Techne | Catalog # 0312

Citations (5)

COA / SDS

Highly potent NMDA agonist

Key Product Details

Purity:	≥98%
Molecular Weight:	143.1 kDa

View Full Technical Details for (RS)-(Tetrazol-5-yl)glycine

Technical Data
Citations

Biological Activity for (RS)-(Tetrazol-5-yl)glycine

(RS)-(Tetrazol-5-yl)glycine is a potent NMDA receptor agonist, approximately 20 times more active than NMDA.

Technical Data for (RS)-(Tetrazol-5-yl)glycine

M. Wt	143.1 kDa
Formula	C₃H₅N₅O₂
Storage	Store at RT
Purity	≥98%
CAS Number	138199-51-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for (RS)-(Tetrazol-5-yl)glycine

Solubility

Soluble Soluble to 50 mM in water

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References for (RS)-(Tetrazol-5-yl)glycine

References are publications that support the biological activity of the product.

Fox JT, Sakamuru S, Huang R High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. 2012 PMID: 22431602
Arnt et al. Diffentiation of in vivo effects of AMPA and NMDA receptor ligands using drug discrimination methods and convulsant/anticonvulsant activity. Eur.J.Pharmacol., 1995;285:289 PMID: 8575516
Moroni et al. NMDA receptor heterogeneity in mammalian tissues: focus on two agonists, (2S,3R,4S)cyclopropylglutamate and the sulfate ester of 4-hydroxy-(S)-pipecolic acid. Naunyn Schmiedebergs Arch.Pharmacol., 1995;351:371 PMID: 7543185
Schoepp et al. D,L-(Tetrazol-5-yl)glycine a novel and highly potent NMDA receptor agonist. Eur.J.Pharmacol., 1991;203:237 PMID: 1686860