(+)-SK&F 10047 hydrochloride

Name: (+)-SK&F 10047 hydrochloride
Brand: Tocris Bioscience
SKU: 1079

Tocris Bioscience, part of Bio-Techne | Catalog # 1079

Citations (5)

COA / SDS

σ1 selective agonist

Key Product Details

Chemical Name:	(2S,6S,11S)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-propenyl)-2,6-methano-3-benzazocin-8-ol hydrochloride
Purity:	≥98%

View Full Technical Details for (+)-SK&F 10047 hydrochloride

Technical Data
Citations

Biological Activity for (+)-SK&F 10047 hydrochloride

(+)-SK&F 10047 hydrochloride is a prototypical σ₁ receptor agonist. Behaviorally active in animal models of memory and stress.

Technical Data for (+)-SK&F 10047 hydrochloride

Formula	C₁₇H₂₃NO.HCl
Storage	Desiccate at +4°C
Purity	≥98%
CAS Number	133005-41-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for (+)-SK&F 10047 hydrochloride

Solubility

Soluble Soluble to 100 mM in water and to 100 mM in DMSO

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References for (+)-SK&F 10047 hydrochloride

References are publications that support the biological activity of the product.

Fox JT, Sakamuru S, Huang R High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. 2012 PMID: 22431602
Kamei et al. (+)-SKF-10,047 and dextromethorphan ameliorate conditioned fear stress via DArgic systems linked to phenytoin-regulated σ₁ sites. Eur.J.Pharmacol., 1996;309:149 PMID: 8874133
Matsuno et al. Involvement of σ₁ receptor in (+)-N-allylnormetazocine-stimulated hippocampal cholinergic functions in rats. Brain Res., 1995;690:200 PMID: 8535837
Walker et al. Sigma receptors: biology and function. Pharmacol.Rev., 1990;42:355 PMID: 1964225

(+)-SK&F 10047 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 1079

Key Product Details

Biological Activity for (+)-SK&F 10047 hydrochloride

Technical Data for (+)-SK&F 10047 hydrochloride

Solubility for (+)-SK&F 10047 hydrochloride

Dilution Calculator

Reconstitution Calculator

References for (+)-SK&F 10047 hydrochloride

Product Documents for (+)-SK&F 10047 hydrochloride

COA

Certificate of Analysis

SDS

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