WIN 55,212-2 mesylate

Biological Activity for WIN 55,212-2 mesylate

Technical Data for WIN 55,212-2 mesylate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for WIN 55,212-2 mesylate

References for WIN 55,212-2 mesylate

References are publications that support the biological activity of the product.

• Chen, Meng, Wan, Yehong, Ade, Kristen, Ting, Jonathan, Feng, Guoping, Calakos, Nicole Sapap3 deletion anomalously activates short-term endocannabinoid-mediated synaptic plasticity. J Neurosci, 2011;31(26):9563-73. 2011 PMID: 21715621
• AN Pushkin, AJ Eugene, V Lallai, A Torres-Men, JP Fowler, E Chen, CD Fowler Cannabinoid and nicotine exposure during adolescence induces sex-specific effects on anxiety- and reward-related behaviors during adulthood PLoS ONE, 2019;14(1):e0211346. 2019 PMID: 30703155
• Y Kong, W Wang, C Zhang, Y Wu, Y Liu, X Zhou Cannabinoid WIN?55,212?2 mesylate inhibits ADAMTS?4 activity in human osteoarthritic articular chondrocytes by inhibiting expression of syndecan?1 Mol Med Rep, 2016;0(0):. 2016 PMID: 27082728
• D'Ambra et al. Conformationally restrained analogues of pravadoline: nanomolar potent, enantioselective, (aminoalkyl)indole agonists of the cannabinoid receptor. J.Med.Chem., 1992;35:124 PMID: 1732519
• Griffin et al. Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5'-O-(3-[35S]thio)-triphosphate binding assay in rat cerebellar membranes. J.Pharmacol.Exp.Ther., 1998;285:553 PMID: 9580597
• Felder et al. Comparison of the pharmacology and signal transduction of the human cannabinoid CB₁ and CB₂ receptors. Mol.Pharmacol., 1995;48:443 PMID: 7565624
• Martellotta et al. Self-administration of the cannabinoid receptor agonist WIN 55,212-2 in drug naive mice. Neuroscience, 1998;85:327 PMID: 9622233