Webinar: Do Human Endogenous Retroviruses (HERVs) Contribute to COVID-19 Immunopathology?

Human Endogenous Retroviruses (HERVs) have been described as genetic elements present in the human genome arising from the integration and ancestral fixing of proviruses in our genome. HERV-W was shown to be directly activated by exogenous viruses (including SARS-CoV-2) with various outcomes depending on triggering viruses and susceptible cells or tissues. In this webinar we demonstrate for the first time an elevated expression of the HERV-W ENV protein in the blood cells and sera of COVID-19 patients (detection on Simple Western™ capillary based immunoassay). We also discuss how we are currently developing a detection system for anti-SARS-CoV-2 IgMs for use on Simple Western, which could complement the SARS-CoV-2 Multi-Antigen Serology Module, which is based solely on the detection of IgGs.

SPEAKER

Benjamin Charvet, Ph.D., Preclinical Project Manager, Geneuro.