ALDH2 Antibody (OTI4H2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-02102

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Mouse

Applications

Validated:

Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG3 Clone # OTI4H2

Concentration

1 mg/ml

View all ALDH2 Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human ALDH2 (NP_000681) produced in HEK293T cell.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3

Theoretical MW

54.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ALDH2 Antibody (OTI4H2)

Immunocytochemistry/Immunofluorescence: ALDH2 Antibody (4H2) [NBP2-02102] Staining of COS7 cells transiently transfected by pCMV6-ENTRY ALDH2.
Flow Cytometry: ALDH2 Antibody (OTI4H2) [NBP2-02102]

Flow Cytometry: ALDH2 Antibody (OTI4H2) [NBP2-02102]

Flow Cytometry: ALDH2 Antibody (4H2) [NBP2-02102] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-ALDH2 antibody, and then analyzed by flow cytometry.
Immunocytochemistry/ Immunofluorescence: ALDH2 Antibody (OTI4H2) [NBP2-02102]

Immunocytochemistry/ Immunofluorescence: ALDH2 Antibody (OTI4H2) [NBP2-02102]

Immunocytochemistry/Immunofluorescence: ALDH2 Antibody (4H2) [NBP2-02102] - Immunofluorescent staining of HepG2 cells using anti-ALDH2 mouse monoclonal antibody.

Applications for ALDH2 Antibody (OTI4H2)

Application
Recommended Usage

Flow Cytometry

1:100

Immunocytochemistry/ Immunofluorescence

1:50-100

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ALDH2

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Long Name

Aldehyde Dehydrogenase 2 Family Member

Alternate Names

ALDHI, ALDM

Entrez Gene IDs

217 (Human)

Gene Symbol

ALDH2

Additional ALDH2 Products

Product Documents for ALDH2 Antibody (OTI4H2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ALDH2 Antibody (OTI4H2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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