Carbonic Anhydrase VIII/CA8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-54947

Novus Biologicals, part of Bio-Techne
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NBP1-54947
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all Carbonic Anhydrase VIII/CA8 Antibodies »

Product Summary for Carbonic Anhydrase VIII/CA8 Antibody

Immunogen

Synthetic peptides corresponding to CA8(carbonic anhydrase VIII) The peptide sequence was selected from the N terminal of CA8. Peptide sequence YEEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDC. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

32 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Carbonic Anhydrase VIII/CA8 Antibody

Western Blot: Carbonic Anhydrase VIII/CA8 Antibody [NBP1-54947]

Western Blot: Carbonic Anhydrase VIII/CA8 Antibody [NBP1-54947]

Western Blot: Carbonic Anhydrase VIII/CA8 Antibody [NBP1-54947] - Titration: 5.0ug/ml Positive Control: SK-MEL-2 cell lysate.

Applications for Carbonic Anhydrase VIII/CA8 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Carbonic Anhydrase VIII/CA8

CA8 was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, CA8 lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). CA8 continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family.The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.

Alternate Names

CA8, CALS, CARP

Gene Symbol

CA8

UniProt

P35219

Additional Carbonic Anhydrase VIII/CA8 Products

Product Documents for Carbonic Anhydrase VIII/CA8 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Carbonic Anhydrase VIII/CA8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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