CEACAM1/CD66a Antibody (11-1H) - BSA Free, Novus Biologicals

Bio-Techne includes Novus Biologicals | Catalog # NBP2-59674

Key Product Details

Species Reactivity

Validated:

Rat

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 11-1H

Format

BSA Free

Concentration

1 mg/ml

View all CEACAM-1/CD66a Antibodies »

Product Summary for CEACAM1/CD66a Antibody (11-1H) - BSA Free

Immunogen

Recombinant soluble rat CEACAM1/CD66a-Fc produced in HEK293 cells

Specificity

Does not cross-react with human CEACAM-1, -3. -4, -5, -6, 7 and -8, mouse CEACAM1 and mouse CEACAM2. Does not bind to the N-domain of rat CEACAM1.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for CEACAM1/CD66a Antibody (11-1H) - BSA Free

Western Blot: CEACAM1/CD66a Antibody (11-1H) [NBP2-59674] - Western Blot
Immunohistochemistry: CEACAM1/CD66a Antibody (11-1H) [NBP2-59674] - IHC
Flow Cytometry: CEACAM1/CD66a Antibody (11-1H) [NBP2-59674] - Flow cytometry
View 2 more images

Applications for CEACAM1/CD66a Antibody (11-1H) - BSA Free

Application
Recommended Usage

ELISA

1:100 - 1:2000

Flow Cytometry

1:10 - 1:1000

Immunohistochemistry

1:10 - 1:500

Immunoprecipitation

1:10 - 1:500

Western Blot

1:100 - 1:2000
Application Notes
Positive Control: lysate from rat bladder cell line endogenously expressing rat CEACAM1/CD66a
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CEACAM-1/CD66a

CEACAM1 encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of only two has been determined. [provided by RefSeq]

Long Name

Carcinoembryonic Antigen-related Cell Adhesion Molecule 1

Alternate Names

BGP1, Biliary Glycoprotein 1, CD66a, Cea-1, CEACAM1, Hv-1, Hv-2, MHVR

Gene Symbol

CEACAM1

Additional CEACAM-1/CD66a Products

Product Documents for CEACAM1/CD66a Antibody (11-1H) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CEACAM1/CD66a Antibody (11-1H) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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