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Dystrobrevin beta Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16246

Novus Biologicals, part of Bio-Techne
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NBP2-16246

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (98%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Dystrobrevin beta Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Dystrobrevin beta. The exact sequence is proprietary.

Localization

Cytoplasm

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

71 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Dystrobrevin beta Antibody

Western Blot: Dystrobrevin beta Antibody [NBP2-16246]

Western Blot: Dystrobrevin beta Antibody [NBP2-16246]

Western Blot: Dystrobrevin beta Antibody [NBP2-16246] - Sample (50 ug of whole cell lysate) A: Mouse Muscle, 7. 5% SDS PAGE gel, diluted at 1:3000.
Immunohistochemistry-Paraffin: Dystrobrevin beta Antibody [NBP2-16246]

Immunohistochemistry-Paraffin: Dystrobrevin beta Antibody [NBP2-16246]

Immunohistochemistry-Paraffin: Dystrobrevin beta Antibody [NBP2-16246] - Human gastric cancer, using Dystrobrevin beta antibody at 1:500 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

Applications for Dystrobrevin beta Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Dystrobrevin beta

This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Alternate Names

beta-dystrobrevin, DTN-B, dystrobrevin beta, dystrobrevin, beta, MGC17163, MGC57126

Gene Symbol

DTNB

UniProt

Additional Dystrobrevin beta Products

Product Documents for Dystrobrevin beta Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Dystrobrevin beta Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.