HBsAg Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-62647

Novus Biologicals, part of Bio-Techne
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NB100-62647-0.1ml
NB100-62647
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Key Product Details

Species Reactivity

Virus

Applications

ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

4.0 mg/ml

View all HBsAg Antibodies »

Product Specifications

Immunogen

Hepatitis B Surface Antigen Subtypes AD & AY

Specificity

NB100-62647 is specific for Hepatitis B surface antigen (HBsAg), a protein component of the viral envelope which is predominantly expressed in the cytoplasm of infected cells. Hep B is a major causative agent of acute and chronic liver disease in humans.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for HBsAg Antibody

Application
Recommended Usage

ELISA

1:200 - 1:1000

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

4.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HBsAg

Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.

Alternate Names

HBsAg, HBV major surface antigen, HBV surface antigen, Hepatitis B Virus major surface antigen, Hepatitis B Virus Surface Antigen, Major surface antigen, protein S

Gene Symbol

S

Additional HBsAg Products

Product Documents for HBsAg Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HBsAg Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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