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Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Antibody

Bio-Techne includes R&D Systems | Catalog # MAB9718

Recombinant Monoclonal Antibody For Research Use Only
Discontinued Product
MAB9718 has been discontinued. View all IGF-I R/IGF1R products.

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Mouse

Applications

Validated:

Flow Cytometry

Cited:

Immunohistochemistry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # Hu14

Product Summary for Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Antibody

Immunogen

Human IGF-I R/IGF1R

Specificity

Detects human IGF-I R/IGF1R based on Teprotumumab therapeutic antibody. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Teprotumumab. This product is for research use only.

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Scientific Data Images for Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Antibody

Detection of IGF-I R/IGF1R antibody in MCF-7 Human Cell Line antibody by Flow Cytometry.

Detection of IGF-I R/IGF1R in MCF-7 Human Cell Line by Flow Cytometry.

MCF-7 human cell line was stained with Human Anti-Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Monoclonal Antibody (Catalog # MAB9718, filled histogram) or irrelevant antibody (open histogram) followed by APC-conjugated Anti-Human IgG Secondary Antibody (Catalog # F0135). View our protocol for Staining Membrane-associated Proteins.

Applications for Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Antibody

Application
Recommended Usage

Flow Cytometry

0.25 µg/106 cells
Sample: MCF-7 Human Cell Line
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Endotoxin Level

<0.10 EU per 1 μg of the antibody by the LAL method.

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IGF-I R/IGF1R

Teprotumumab is a biosimilar directed against the extracellular domain of IGF-I R/IGF1R. This product constitutes the immunogen used for the anti-Idiotype catalog number MAB9634.

Long Name

Insulin-like Growth Factor I Receptor

Alternate Names

CD221, IGF-1R, IGF-IR, IGF1R, IGFIR

Entrez Gene IDs

3480 (Human)

Gene Symbol

IGF1R

Additional IGF-I R/IGF1R Products

Product Documents for Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Antibody

For research use only

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