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Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Biotinylated Antibody

Bio-Techne includes R&D Systems | Catalog # FAB9718B

Recombinant Monoclonal Antibody For Research Use Only
Discontinued Product
FAB9718B has been discontinued. View all IGF-I R/IGF1R products.

Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry

Label

Biotin

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # Hu14

Product Summary

Immunogen

Human IGF-I R/IGF1R

Specificity

Detects human IGF-I R/IGF1R based on Teprotumumab therapeutic antibody. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Teprotumumab. This product is for research use only.

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Scientific Data Images

Detection of IGF-I R/IGF1R antibody in MCF-7 human breast adenocarcinoma cell line antibody by Flow Cytometry.

Detection of IGF-I R/IGF1R in MCF-7 human breast adenocarcinoma cell line by Flow Cytometry.

MCF-7 human breast adenocarcinoma cell line was stained with Human Anti-Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Biotinylated Monoclonal Antibody (Catalog # FAB9718B, filled histogram) or irrelevant biotinylated antibody (open histogram) followed by APC-conjugated Streptavidin (Catalog # F0050). View our protocol for Staining Membrane-associated Proteins.

Applications

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: MCF-7 human breast adenocarcinoma cell line
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: IGF-I R/IGF1R

Teprotumumab is a biosimilar directed against the extracellular domain of IGF-I R/IGF1R. The biotinylated antibody can be used in flow cytometry or various assay format to measure IGF-I R/IGF1R expression and can be detected by conjugated streptavidin.

Long Name

Insulin-like Growth Factor I Receptor

Alternate Names

CD221, IGF-1R, IGF-IR, IGF1R, IGFIR

Entrez Gene IDs

3480 (Human)

Gene Symbol

IGF1R

Additional IGF-I R/IGF1R Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices

For research use only

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