Human Integrin alpha4/CD49d APC-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB1354A
Discontinued Product
FAB1354A has been discontinued.
View all Integrin alpha 4/CD49d products.
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Flow Cytometry
Cited:
Flow Cytometry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Mouse IgG1 Clone # 7.2R
Product Specifications
Immunogen
DX-3 human melanoma cell line
Specificity
Detects the human Integrin alpha4/CD49d subunit in flow cytometry.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Scientific Data Images for Human Integrin alpha4/CD49d APC-conjugated Antibody
Detection of Integrin alpha4/CD49d in Human Blood Lymphocytes by Flow Cytometry.
Human peripheral blood lymphocytes were stained with Mouse Anti-Human Integrin a4/CD49d APC-conjugated Monoclonal Antibody (Catalog # FAB1354A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.Applications for Human Integrin alpha4/CD49d APC-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: Human peripheral blood lymphocytes
Sample: Human peripheral blood lymphocytes
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Background: Integrin alpha 4/CD49d
The Integrin alpha4 subunit, also known as CD49d and VLA-4 alpha subunit, forms heterodimers with Integrin beta1 (CD29) or beta7. Integrins alpha4 beta1 (VLA4) and alpha4 beta7 are both receptors for fibronectin and VCAM. Integrin alpha4 beta7 also binds the mucosal addressin cell adhesion molecule (MAdCAM-1). On the cell surface, VLA4 will participate in homotypic binding between endothelial cells and leukocytes. The extracellular domains of human and mouse Integrin alpha4 share 85% aa sequence identity.
Alternate Names
CD49d, ITGA4, VLA-4
Gene Symbol
ITGA4
Additional Integrin alpha 4/CD49d Products
Product Documents for Human Integrin alpha4/CD49d APC-conjugated Antibody
Product Specific Notices for Human Integrin alpha4/CD49d APC-conjugated Antibody
For research use only
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