IBRDC2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-37941

Novus Biologicals, part of Bio-Techne
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NBP2-37941
NBP2-37941-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IBRDC2 Antibodies »

Product Summary for IBRDC2 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: MGSAGRLHYLAMTAENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IBRDC2 Antibody

Immunohistochemistry-Paraffin: IBRDC2 Antibody [NBP2-37941]

Immunohistochemistry-Paraffin: IBRDC2 Antibody [NBP2-37941]

Immunohistochemistry-Paraffin: IBRDC2 Antibody [NBP2-37941] - Staining of human colon shows strong cytoplasmic positivity in glandular cells.

Applications for IBRDC2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IBRDC2

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, therebypromoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism

Alternate Names

bA528A10.3, E3 ubiquitin-protein ligase RNF144B, EC 6.3.2, EC 6.3.2.-, IBR domain containing 2, IBR domain-containing protein 2, IBRDC2, KIAA0161, p53-inducible RING finger protein, p53RFP, PIR2, ring finger protein 144BMGC71786

Gene Symbol

RNF144B

UniProt

Q7Z419 (Human)

Additional IBRDC2 Products

Product Documents for IBRDC2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IBRDC2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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