MIS/AMH Antibody (14)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11761

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-11761
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse Clone # 14

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MIS/AMH Antibodies »

Product Summary for MIS/AMH Antibody (14)

Immunogen

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MIS/AMH (Accession#: NP_000470.2; Leu25-Arg560).

Clonality

Monoclonal

Host

Mouse

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for MIS/AMH Antibody (14)

Immunohistochemistry-Paraffin: MIS/AMH Antibody (14) [NBP3-11761]

Immunohistochemistry-Paraffin: MIS/AMH Antibody (14) [NBP3-11761]

Immunohistochemistry-Paraffin: MIS/AMH Antibody (14) [NBP3-11761] - Immunochemical staining of human AMH in human testis with mouse monoclonal antibody at 1:30 dilution, formalin-fixed paraffin embedded sections.

Applications for MIS/AMH Antibody (14)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:20-1:50
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MIS/AMH

Müllerian inhibiting substance (MIS), also named anti-Müllerian hormone (AMH), is a tissue-specific TGF-beta superfamily growth factor. Its expression is restricted to Sertoli cells of fetal and postnatal testis, and to granulosa cells of postnatal ovary. MIS is synthesized and secreted as a disulfide-linked homodimeric propeptide. Proteolytic cleavage is required to separate the N-terminal proregion from the C-terminal bioactive peptide. Both fragments remain associated in a non-covalent complex. The C-terminal sequence forms a cysteine knot via seven canonical cysteine residues found in TGF-beta superfamily members.

Long Name

Mullerian-inhibiting Substance/Anti-Mullerian Hormone

Alternate Names

AMH

Gene Symbol

AMH

Additional MIS/AMH Products

Product Documents for MIS/AMH Antibody (14)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MIS/AMH Antibody (14)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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