Mouse CD161/NK1.1 APC‑conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB8319A
Discontinued Product
FAB8319A has been discontinued.
View all CD161/NK1.1 products.
Key Product Details
Species Reactivity
Mouse
Applications
Flow Cytometry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Mouse IgG2A Clone # PK136
Product Specifications
Immunogen
Mouse NK-1+ splenocytes and bone marrow cells
Specificity
Detects mouse CD161/NK1.1 by flow cytometry
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Scientific Data Images for Mouse CD161/NK1.1 APC‑conjugated Antibody
Detection of CD161/NK1.1 in C57BL/6 Mouse Splenocytes by Flow Cytometry.
C57BL/6 mouse splenocytes were stained with Rat Anti-Mouse NKp46/NCR1 PE-conjugated Monoclonal Antibody (Catalog # FAB22252P) and either (A) Mouse Anti-Mouse CD161/NK1.1 APC-conjugated Monoclonal Antibody (Catalog # FAB8319A) or (B) Mouse IgG2AAllophycocyanin Isotype Control (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.Applications for Mouse CD161/NK1.1 APC‑conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: C57BL/6 mouse splenocytes
Sample: C57BL/6 mouse splenocytes
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CD161/NK1.1
CD161, also known as NK1.1, KLRB-1C, Ly-55, and NKR-P1c, is a 28 kDa type 2 transmembrane protein in the Killer Cell Lectin-like Receptor family. CD161 is expressed as a disulfide-linked homodimer on the surface of NK cells and subpopulations of NKT, CD4+, CD8+, and gamma/ delta T cells. Its cross-linking on NK cells induces cytolytic activity, and on CD4 cells it promotes IgE production and the expansion of Th2 responses. Mature mouse CD161 consists of a 45 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 157 aa extracellular domain with one C-type lectin domain.
Additional CD161/NK1.1 Products
Product Documents for Mouse CD161/NK1.1 APC‑conjugated Antibody
Product Specific Notices for Mouse CD161/NK1.1 APC‑conjugated Antibody
For research use only
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