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NKX6.1 Antibody (NKX61/2561) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-79872

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array, SDS-Page

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2c Kappa Clone # NKX61/2561

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Recombinant full-length human NKX6.1 protein (Uniprot: P78426)

Localization

Nuclear

Marker

Marker for Pancreatic and Duodenal Neuroendocrine Tumors

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2c Kappa

Description

1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP2-79737).

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for NKX6.1 Antibody (NKX61/2561) - Azide and BSA Free

Immunohistochemistry-Paraffin: NKX6.1 Antibody (NKX61/2561) - Azide and BSA Free [NBP2-79872]

Immunohistochemistry-Paraffin: NKX6.1 Antibody (NKX61/2561) - Azide and BSA Free [NBP2-79872]

Immunohistochemistry-Paraffin: NKX6.1 Antibody (NKX61/2561) - Azide and BSA Free [NBP2-79872] - Formalin-fixed, paraffin-embedded human pancreas stained with NKX6.1 Mouse Monoclonal Antibody (NKX61/2561).
Immunohistochemistry-Paraffin: NKX6.1 Antibody (NKX61/2561) - Azide and BSA Free [NBP2-79872]

Immunohistochemistry-Paraffin: NKX6.1 Antibody (NKX61/2561) - Azide and BSA Free [NBP2-79872]

Immunohistochemistry-Paraffin: NKX6.1 Antibody (NKX61/2561) - Azide and BSA Free [NBP2-79872] - Formalin-fixed, paraffin-embedded human pancreas stained with NKX6.1 mouse monoclonal antibody (NKX61/2561).
Protein Array: NKX6.1 Antibody (NKX61/2561) - Azide and BSA Free [NBP2-79872]

Protein Array: NKX6.1 Antibody (NKX61/2561) - Azide and BSA Free [NBP2-79872]

Protein Array: NKX6.1 Antibody (NKX61/2561) - Azide and BSA Free [NBP2-79872] - Protein Array containing more than 19,000 full-length human proteins using NKX6.1 Mouse MAb. The Z-score represents the strength of signal that a monoclonal antibody (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a protein. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets are arranged in descending order of the Z-score, the S-score is the difference between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Applications for NKX6.1 Antibody (NKX61/2561) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

1 - 2 ug/mL

Immunohistochemistry-Paraffin

1 - 2 ug/mL
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: NKX6.1

In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM]

Long Name

NK6 Homeobox 1

Alternate Names

NKX6-1, NKX6A

Gene Symbol

NKX6-1

Additional NKX6.1 Products

Product Documents for NKX6.1 Antibody (NKX61/2561) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NKX6.1 Antibody (NKX61/2561) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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