Phosphoserine Antibody [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1981

Novus Biologicals, part of Bio-Techne
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NB100-1981
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Non-species specific

Cited:

Human

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Knockdown Validated

Cited:

Western Blot

Label

HRP

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Phosphoserine Antibodies »

Product Specifications

Immunogen

Phosphoserine conjugated to KLH, and phosvitin mixture

Specificity

Recognizes proteins phosphorylated on serine residues. Does not cross-react with phosphotyrosine.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Phosphoserine Antibody [HRP]

Western Blot: Phosphoserine Antibody [HRP] [NB100-1981] - Phosphoserine Antibody [NB100-1981] - Western blot analysis of human MMRU melanoma cells probed with Phosphoserine polyclonal antibody. Top (from the left): MMRU cells treated with 0 (A), 50 (B), 200 (C), 400 (D) l long wavelength UV, or 0.1uM of okadaic acid (E) Bottom: Same samples, except probed with b-actin antibody

Applications for Phosphoserine Antibody [HRP]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

HRP stabilizing buffe rcontains PBS, 0.1% BSA, 50% Glycerol

Preservative

0.01% Proclin

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Phosphoserine

Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently attaching it to a recipient protein that acts as a substrate. Most kinases act on both serine and threonine; others act on tyrosine, and a number (dual specificity kinases) act on all three. Because phosphorylation can occur at multiple sites on any given protein, it can therefore change the function or localization of that protein at any time (1). Changing the function of these proteins has been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders (2-4).

Alternate Names

Phosphoserine; Phosphothreonine

Additional Phosphoserine Products

Product Documents for Phosphoserine Antibody [HRP]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Phosphoserine Antibody [HRP]

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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