PTP sigma/PTPRS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-55570

Novus Biologicals, part of Bio-Techne
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NBP2-55570-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PTP sigma/PTPRS Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: KPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTASGVHK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PTP sigma/PTPRS Antibody

Immunocytochemistry/ Immunofluorescence: PTP sigma/PTPRS Antibody [NBP2-55570]

Immunocytochemistry/ Immunofluorescence: PTP sigma/PTPRS Antibody [NBP2-55570]

Immunocytochemistry/Immunofluorescence: PTP sigma/PTPRS Antibody [NBP2-55570] - Staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.

Applications for PTP sigma/PTPRS Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PTP sigma/PTPRS

The protein encoded by the PTPRS gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. (provided by RefSeq)

Long Name

Protein Tyrosine Phosphatase Receptor-type Sigma

Alternate Names

PTPR sigma, PTPRS

Gene Symbol

PTPRS

Additional PTP sigma/PTPRS Products

Product Documents for PTP sigma/PTPRS Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PTP sigma/PTPRS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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