Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all SLX4 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1650 and 1700 of human SLX4 using the numbering given in entry NP_115820.2 (GeneID 84464).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SLX4 Antibody

Immunoprecipitation: SLX4 Antibody [NBP1-28679]

Immunoprecipitation: SLX4 Antibody [NBP1-28679]

Immunoprecipitation: BTBD12 Antibody [NBP1-28679] - Detection of human BTBD12 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-BTBD12 antibody NBP1-28679 used for IP at 6 ug per reaction. BTBD12 was also immunoprecipitated by another rabbit anti-BTBD12 antibody. For blotting immunoprecipitated BTBD12, NBP1-28679 was used at 3 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Applications for SLX4 Antibody

Application
Recommended Usage

Immunohistochemistry

Reported in (PMID: 21655083)

Immunoprecipitation

2 - 10 ug/mg lysate

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: SLX4

BTBD12 (BTBD12 domain-containing protein 12) has been identified as the human ortholog of the yeast Slx4p and drosophila MUS312 DNA repair factors. BTBD12 is an ATM/ATR checkpoint substrate that functions as part of a Holliday junction resolvase and is important for DNA interstrand crosslink repair.

Long Name

SLX4 Structure-Specific Endonuclease Subunit

Alternate Names

BTBD12, FANCP, KIAA1784, KIAA1987

Entrez Gene IDs

84464 (Human)

Gene Symbol

SLX4

UniProt

Q8IY92 (Human)

Additional SLX4 Products

Product Documents for SLX4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SLX4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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