SOS1 Antibody (SOS-01) [Janelia Fluor® 635]

Novus Biologicals, part of Bio-Techne | Catalog # NB110-68800JF635

Novus Biologicals, part of Bio-Techne
Discontinued Product
NB110-68800JF635 has been discontinued. View all SOS1 products.

Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Janelia Fluor 635

Antibody Source

Monoclonal Mouse IgG1 Clone # SOS-01

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all SOS1 Antibodies »

Product Specifications

Immunogen

Peptide corresponding to amino acids THPSMHRDGPPLLENAHSS of human Sos protein (NM_005633.3)

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Specificity

The SOS-01 reacts with human Sos, an ubiquitously expressed 150 kDa intracellular protein.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for SOS1 Antibody (SOS-01) [Janelia Fluor® 635]

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: SOS1

SOS1 encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq]

Long Name

Son of sevenless homolog 1

Alternate Names

SOS-1

Gene Symbol

SOS1

Additional SOS1 Products

Product Documents for SOS1 Antibody (SOS-01) [Janelia Fluor® 635]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SOS1 Antibody (SOS-01) [Janelia Fluor® 635]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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