VEGF-C Antibody (MM0006-2E65) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB110-60971

Novus Biologicals, part of Bio-Techne
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NB110-60971
NB110-60971-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2 Clone # MM0006-2E65

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all VEGF-C Antibodies »

Product Specifications

Immunogen

Human recombinant VEGF-C

Specificity

No cross-reactivity is shown with human VEGFA, VEGF-B and VEGF-D.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2

Scientific Data Images for VEGF-C Antibody (MM0006-2E65) - Azide and BSA Free

Immunohistochemistry-Paraffin: VEGF-C Antibody (MM0006-2E65) - Azide and BSA Free [NB110-60971]

Immunohistochemistry-Paraffin: VEGF-C Antibody (MM0006-2E65) - Azide and BSA Free [NB110-60971]

Immunohistochemistry-Paraffin: VEGF-C Antibody (MM0006-2E65) [NB110-60971] - Formalin fixed and paraffin embedded normal human placenta tissue is subjected to mouse anti human VEGF-C

Applications for VEGF-C Antibody (MM0006-2E65) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

1:25 - 1:50

Immunohistochemistry-Paraffin

1:25 - 1:50

Western Blot

1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: VEGF-C

Vascular endothelial growth factors (VEGFs), also known as vasculotropins, are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimulate the proliferation of endothelial cells, induce angiogenesis, promote cell migration, increase vascular permeability, and inhibit apoptosis. The mitogenic activity of VEGFs appears to be mediated by specific VEGF receptors. The target cell specificity of VEGF is restricted to vascular endothelial cells. Vascular Endothelial Growth Factor C (VEGFC) is a member of the VEGF subfamily of PDGF-related growth factors. It is the ligand for Flt4 (VEGFR3) and KDR (VEGFR2). VEGFC binds Flt4 and induces tyrosine autophosphorylation of VEGFR3 and VEGFR2. VEGFC also stimulates the migration of bovine capillary endothelial cells in collagen gel. It is a specific growth factor for the lymphatic vascular system and mediates lymphangiogenesis. VEGFC is abundantly expressed in heart and skeletal muscle. Other tissues such as lung and kidney also express VEGFC. The human VEGFC gene is located on chromosome 4q34.

Long Name

Vascular Endothelial Growth Factor C

Alternate Names

VEGFC

Entrez Gene IDs

7424 (Human)

Gene Symbol

VEGFC

UniProt

P49767 (Human)

Additional VEGF-C Products

Product Documents for VEGF-C Antibody (MM0006-2E65) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for VEGF-C Antibody (MM0006-2E65) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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