Non-human Primate IL-10 ELISA Development Kit

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18276

Novus Biologicals, part of Bio-Techne
Discontinued Product
NBP3-18276 has been discontinued. View all IL-10 products.

Key Product Details

Reactivity

Non-human Primate

View all IL-10 ELISA Kits »

Product Specifications

Conjugate

Unconjugated

Specificity

The kit contains a matched pair of monoclonal antibodies (mAbs) specific for IL-10 from rhesus macaque, cynomolgus macaque, and common marmoset.

Scientific Data Images for Non-human Primate IL-10 ELISA Development Kit

ELISA: Non-human Primate IL-10 ELISA Development Kit [NBP3-18276]

ELISA: Non-human Primate IL-10 ELISA Development Kit [NBP3-18276]

ELISA: Non-human Primate IL-10 ELISA Development Kit [NBP3-18276] - Standard Reference Curve

Kit Contents for Non-human Primate IL-10 ELISA Development Kit

  • Biotinylated detection mAb (MT32AD)
  • Capture mAb (MT3515)
  • Recombinant human IL-10 ELISA standard
  • Standard reconstitution buffer
  • Streptavidin-HRP

Preparation and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: IL-10

Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. ILs have a variety of functions, but most function to direct other immune cells to divide and differentiate. Each IL acts on a specific, limited group of cells through a receptor specific for that IL. Human IL10 is a non glycosylated polypeptide consisting of 178 amino acids. There is 73% homology between the human and mouse IL10 proteins, however, the human IL10 acts on both human and mouse target cells, while the mouse IL10 has species specific activity. The cellular sources of IL10 are CD4+ T cells and T cell clones, thymocytes, B cells and B cell lymphomas, macrophages, mast cell lines and keratinocytes. IL10 will stimulate the growth of stem cells, mast cells and thymocytes. IL10 enhances cytotoxic T cell development, and costimulates B cell differentiation and immunoglobulin secretion. IL10 inhibits cytokine production by macrophages and suppresses macrophage class II MHC expression. The human IL10 gene is on human chromosome 1.

Long Name

Interleukin 10

Alternate Names

CSIF, GVHDS, IL10, IL10A, TGIF

Gene Symbol

IL10

Additional IL-10 Products

Product Documents for Non-human Primate IL-10 ELISA Development Kit

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Non-human Primate IL-10 ELISA Development Kit

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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