Quantikine Immunoassay Control Set 1064 for Human HS CTLA-4

Name: Quantikine Immunoassay Control Set 1064 for Human HS CTLA-4
Brand: R&D Systems
SKU: QC283

R&D Systems, part of Bio-Techne | Catalog # QC283

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COA / SDS

For use with catalog number HSCT40

Key Product Details

Technical Data
Citations / Reviews

Summary for Quantikine Immunoassay Control Set 1064 for Human HS CTLA-4

CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.

Product Specifications for Quantikine Immunoassay Control Set 1064 for Human HS CTLA-4

Species	Human
Applications	Control
Source	N/A

Preparation & Storage

Shipping Conditions	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage	Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: CTLA-4

Item	Value
Long Name	Cytotoxic T-lymphocyte-associated Molecule 4
Entrez Gene IDs	1493 (Human); 12477 (Mouse); 403696 (Canine); 102115124 (Cynomolgus Monkey)
Alternate Names	CD, CD152, CD152 antigen, CD152IDDM12, CD28, CELIAC3, CTLA-4, CTLA4, Cytotoxic T-lymphocyte-associated antigen 4, GRD4, GSE, ICOS, celiac disease 3, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4

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Product Documents for Quantikine Immunoassay Control Set 1064 for Human HS CTLA-4

COA

SDS

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