FFN 206 dihydrochloride

Name: FFN 206 dihydrochloride
Brand: Tocris Bioscience
SKU: 5043

Tocris Bioscience, part of Bio-Techne | Catalog # 5043

Citations (2)

COA / SDS

Fluorescent VMAT2 substrate

Key Product Details

Description:	Fluorescent VMAT2 substrate
Chemical Name:	4-(2-Aminoethyl)-7-(methylamino)-2H-1-benzopyran-2-one dihydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	291.17

View Full Technical Details for FFN 206 dihydrochloride

Technical Data
Citations

Biological Activity for FFN 206 dihydrochloride

FFN 206 dihydrochloride is a fluorescent VMAT2 substrate (IC₅₀ app = 1.15 μM). Allows detection of VMAT2 subcellular locations in cell culture. Exhibits no detectable inhibition of DAT. Excitation maximum = 369 nm; emission maximum = 464 nm.

Licensing Information

Sold with the permission of Columbia University

Optical Data for FFN 206 dihydrochloride

Emission Color	Blue
λ_abs	369 nm
λ_em	464 nm
Application	Fluorescence Microscopy, Confocal Microscopy

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Technical Data for FFN 206 dihydrochloride

M. Wt	291.17
Formula	C₁₂H₁₄N₂O₂.2HCl
Storage	Store at -20°C
Purity	≥99% (HPLC)
CAS Number	1883548-88-6
PubChem ID	91826079
InChi Key	ODENAPXTSFPACZ-UHFFFAOYSA-N
Smiles	CNC1=CC=C2C(OC(C=C2CCN)=O)=C1.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for FFN 206 dihydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	29.12	100
	DMSO	14.56	50

Preparing Stock Solutions for FFN 206 dihydrochloride

The following data is based on the product molecular weight 291.17.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.43 mL	17.17 mL	34.34 mL
5 mM	0.69 mL	3.43 mL	6.87 mL
10 mM	0.34 mL	1.72 mL	3.43 mL
50 mM	0.07 mL	0.34 mL	0.69 mL

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References for FFN 206 dihydrochloride

References are publications that support the biological activity of the product.

Hu New fluorescent substrate enables quantitative and high-throughput examination of vesicular monoamine transporter 2 (VMAT2). ACS Chem.Biol. 2013 PMID: 23859623