Taxol Janelia Fluor® 526
Tocris Bioscience, part of Bio-Techne | Catalog # 7315
Key Product Details
| Description: | Green-fluorescent taxol derivative; binds microtubules. Used for: microtubules imaging. Application: confocal microscopy, super resolution microscopy. Suitable for live cell imaging |
| Alternative Names: | Janelia Fluor 526-TXL |
| Chemical Name: | 4-((8-(((1S,2R)-3-(((2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-12-(benzoyloxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-9-yl)oxy)-2-hydroxy-3-oxo-1-phenylpropyl)amino)-8-oxooctyl)carbamoyl)-2-(3-(3,3-difluoroazetidin-1-ium-1-ylidene)-6-(3,3-difluoroazetidin-1-yl)-2,7-difluoro-3H-xanthen-9-yl)benzoate trifluoroacetate |
| Purity: | ≥85% (HPLC) |
| Molecular Weight: | 1507.42 |
Biological Activity for Taxol Janelia Fluor® 526
Key information: Taxol Janelia Fluor® 526 is a fluorogenic, green-fluorescent taxol derivative for direct imaging of the microtubule cytoskeleton. Suitable for live cell imaging.
Used for: direct imaging of the microtubule cytoskeleton.
Application: confocal microscopy, Super Resolution Microscopy (SRM) including STED.
Properties and Photophysical Data: Taxol Janelia Fluor® 526 is fluorogenic: it fluoresces only once bound to microtubules, enabling hassle-free no-wash experiments. Excitation and emission maxima (λ) are 531 nm and 549 nm, respectively; quantum yield = 0.87; extinction coefficient = 118,000 M-1cm-1.
Licensing Information
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus
Optical Data for Taxol Janelia Fluor® 526
| Emission Color | Yellow |
|---|---|
| λabs | 531 nm |
| λem | 549 nm |
| Extinction Coefficient (ε) | 118000 M-1cm-1 |
| Quantum Yield (φ) | 0.87 |
| Application | Confocal Microscopy, Super Resolution Microscopy (SRM), STED |
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