Taxol Janelia Fluor® 646
Tocris Bioscience, part of Bio-Techne | Catalog # 6266
Key Product Details
| Description: | Red-fluorescent taxol derivative. Used for: microtubule staining. Application: confocal microscopy, fluorescence microscopy; protocol available |
| Chemical Name: | 2-(3-(Azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)-4-(((2S)-1-(((2aR,4S,4aS,6R,9S,11S,12S,12bS)-6,12b-diacetoxy-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-4-yl)oxy)-1-oxopropan-2-yl)carbamoyl)benzoate |
| Purity: | ≥95% (HPLC) |
| Molecular Weight: | 1403.62 |
Biological Activity for Taxol Janelia Fluor® 646
Key information: Taxol Janelia Fluor® 646 is a red-fluorescent taxol derivative for direct imaging of the microtubule cytoskeleton.
Used for: microtubule cytoskeleton imaging.
Application: confocal microscopy, fluorescence microscopy.
Properties and Photophysical Data: Excitation and emission maxima (λ) are 655 nm and 671 nm, respectively.
For more information on how Taxol-Janelia Fluor® 646 may be used, see our protocol.
Licensing Information
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus
Optical Data for Taxol Janelia Fluor® 646
| Emission Color | Red |
|---|---|
| λabs | 655 nm |
| λem | 671 nm |
| Application | Fluorescence Microscopy, Confocal Microscopy |
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Application of Taxol Janelia Fluor® 646, dye on COS7 cells. COS7 cells were labeled with 3 µM Taxol Janelia Fluor® 646 for one hour at 37°C. Images were taken on a Leica TCS SP8 Confocal Laser Scanning Microscope. All images kindly provided by Prof. Christian Soeller, University of Exeter; acquired by Evelina Lucinskaite, Anna Meletiou and Alexander Clowsley. |
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