tri-GalNAc-C5-AF647

Name: tri-GalNAc-C5-AF647
Brand: Tocris Bioscience
SKU: 7901

Tocris Bioscience, part of Bio-Techne | Catalog # 7901

COA / SDS

Fluorescent ASGPR ligand. Application: flow cytometry, fluorescence microscopy

Key Product Details

Description:	Fluorescent ASGPR ligand. Application: flow cytometry, fluorescence microscopy
Purity:	≥90%
Molecular Weight:	2456.74

View Full Technical Details for tri-GalNAc-C5-AF647

Technical Data
Citations

Biological Activity for tri-GalNAc-C5-AF647

Key information: tri-GalNAc-C5-AF647 is a fluorescent asialoglycoprotein receptor (ASGPR) ligand. Suitable for live-cell imaging. Can be used for lysosomal uptake imaging in live cells. Also can be used for isolating hepatocytes due to its uptake via ASGPR receptor.

Application: Flow cytometry, fluorescence microscopy.

Properties and Photophysical Data: Suitable for multiplexing and can be combined with DAPI (Cat. No. 5748) counter-staining. Excitation and emission maxima (λ) are 663 and 684 nm, respectively.

Optical Data for tri-GalNAc-C5-AF647

λ_abs	663 nm
λ_em	684 nm
Cell Permeable	Yes
Application	Flow Cytometry, Fluorescence Microscopy

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

Technical Data for tri-GalNAc-C5-AF647

M. Wt	2456.74
Formula	C₁₀₃H₁₆₂N₁₆O₄₄S₄
Storage	Store at -20°C
Purity	≥90%
InChi Key	YADZNIHLQXJZAN-PPECRGGSSA-N
Smiles	O=C(NC(COCC1=CN(N=N1)CCOCCOCCOCCO[C@H]2O[C@H]([C@@H](O)[C@@H](O)[C@@H]2NC(C)=O)CO)(COCC3=CN(N=N3)CCOCCOCCOCCO[C@@H]4O[C@@H]([C@H](O)[C@H](O)[C@H]4NC(C)=O)CO)COCC5=CN(N=N5)CCOCCOCCOCCO[C@H]6O[C@H]([C@@H](O)[C@@H](O)[C@@H]6NC(C)=O)CO)CCCCCNC(CCCCCC7(C(/C=C/C=C/C=C8C(C)(C9=C(N\8CCCS(=O)(O)=O)C=CC(S(=O)(O)=O)=C9)C)=[N+](C%10=C7C=C(C=C%10)S(=O)(O)=O)CCCS(=O)([O-])=O)C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for tri-GalNAc-C5-AF647

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	24.57	10

Preparing Stock Solutions for tri-GalNAc-C5-AF647

The following data is based on the product molecular weight 2456.74.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	4.07 mL	20.35 mL	40.70 mL
0.5 mM	0.81 mL	4.07 mL	8.14 mL
1 mM	0.41 mL	2.04 mL	4.07 mL
5 mM	0.08 mL	0.41 mL	0.81 mL

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Reconstitution Calculator

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References for tri-GalNAc-C5-AF647

References are publications that support the biological activity of the product.

Sanhueza Efficient liver targeting by polyvalent display of a compact ligand for the asialoglycoprotein receptor. J.Am.Chem.Soc. 2017 PMID: 28230359