Recombinant Human IL-28B/IFN-lambda 3 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-52083

Novus Biologicals, part of Bio-Techne
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NBP2-52083-0.25mg
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Key Product Details

Source

Baculovirus

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all IL-28B/IFN-lambda 3 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 22-196 of Human IL-28B/IFN-lambda 3

Source: Baculovirus

Amino Acid Sequence: VPVARLRGAL PDARGCHIAQ FKSLSPQELQ AFKRAKDALE ESLLLKDCKC RSRLFPRTWD LRQLQVRERP VALEAELALT LKVLEATADT DPALGDVLDQ PLHTLHHILS QLRACIQPQP TAGPRTRGRL HHWLHRLQEA PKKESPGCLE ASVTFNLFRL LTRDLNCVAS GDLCVHHHHH H

Purity

>85%, by SDS-PAGE

Endotoxin Level

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Predicted Molecular Mass

20.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human IL-28B/IFN-lambda 3 His Protein

SDS-PAGE: Recombinant Human IL-28B/IFN-lambda 3 His Protein [NBP2-52083]

SDS-PAGE: Recombinant Human IL-28B/IFN-lambda 3 His Protein [NBP2-52083]

SDS-Page: Recombinant Human IL-28B/IFN-lambda 3 Protein [NBP2-52083] - 15% SDS Page (3 ug)

Formulation, Preparation and Storage

NBP2-52083
Formulation PBS (pH 7.4), 20% glycerol, 1 mM EDTA, 0.1 mM PMSF
Preservative No Preservative
Concentration 0.25 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-28B/IFN-lambda 3

Human/mouse IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively.

Long Name

Interleukin 28B

Alternate Names

IFN-lambda 3

Gene Symbol

IFNL3

Additional IL-28B/IFN-lambda 3 Products

Product Documents for Recombinant Human IL-28B/IFN-lambda 3 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human IL-28B/IFN-lambda 3 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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