Simple Plex Control for Human ASC

Name: Simple Plex Control for Human ASC
Brand: ProteinSimple
SKU: 898571

ProteinSimple, part of Bio-Techne | Catalog # 898571

Product Datasheet / COA

Control for use with Human ASC Simple Plex Cartridge Kit

Key Product Details

Technical Data
Citations

Summary for Simple Plex Control for Human ASC

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human ASC concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

ASC contains an N-terminal Pyrin domain and C-terminal CARD (Caspase-recruitment Domain), and is a p53 target protein that serves as an adaptor to the pro-apoptotic Bax molecule. The interaction of ASC with Bax promotes apoptosis in response to many apoptotic stimuli. Methylation of the ASC gene has been correlated with decreased protein expression in numerous types of cancer.

Product Specifications for Simple Plex Control for Human ASC

Species	Human
Applications	Control, Simple Plex Automated Immunoassay
Source	N/A

Preparation & Storage

Shipping Conditions

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Background: ASC

Item	Value
Long Name	Apoptosis-Associated Speck-Like Protein Containing A CARD
Entrez Gene IDs	29108 (Human)
Alternate Names	ASC, CARD5, Caspase recruitment domain-containing protein 5, PYCARD, PYD and CARD domain-containing protein, TMS, TMS-1, TMS1, Target of methylation-induced silencing 1, apoptosis-associated speck-like protein containing a CARD, caspase recruitment domain protein 5, hASC

Product Documents for Simple Plex Control for Human ASC

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