Summary for Simple Plex Control for Human CCL18/PARC
INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human CCL18/PARC concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.
Pulmonary and activation-regulated chemokine (PARC), also known as alternative macrophage activation-associated CC chemokine (AMAC)-1, macrophage inflammatory protein (MIP)-4, and dendritic cell chemokine (DC-CK1), is a novel CC chemokine that is highly homologous to MIP-1 alpha (61% amino acid sequence identity). In vitro, PARC mRNA expression is induced in alternatively activated macrophages by Th2 cytokines such as IL-4, IL-10 and IL-13, and inhibited by IFN-gamma.
Product Specifications for Simple Plex Control for Human CCL18/PARC
Species
Human
Applications
Control, Simple Plex Automated Immunoassay
Source
N/A
Preparation & Storage
Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt. • Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended. • Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: CCL18/PARC
Item
Value
Entrez Gene IDs
6362 (Human)
Alternate Names
AMAC-1, AMAC-1Small-inducible cytokine A18, AMAC1CC chemokine ligand 18, Alternative macrophage activation-associated CC chemokine 1, CCL18, CKb7, DC-CK1, DC-CK1CC chemokine PARC, DCCK1Macrophage inflammatory protein 4, Dendritic cell chemokine 1, MIP-4, MIP-4C-C motif chemokine 18, MIP4, PARC, PARCPulmonary and activation-regulated chemokine, SCYA18chemokine (C-C), dendritic, chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated), small inducible cytokine A18, small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary andactivation-regulated
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