Simple Plex Control for Human CXCL13/BLC/BCA-1

Name: Simple Plex Control for Human CXCL13/BLC/BCA-1
Brand: ProteinSimple
SKU: 898173

ProteinSimple, part of Bio-Techne | Catalog # 898173

Product Datasheet / COA

Control for use with Human and Non-Human Primate CXCL13/BLC/BCA-1 Simple Plex Cartridge Kit

Summary for Simple Plex Control for Human CXCL13/BLC/BCA-1

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human and NHP CXCL13/BLC/BCA-1 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

CXCL13/BLC/BCA-1 is a constitutively expressed chemokine that plays an important role in B and T cell homing. It is expressed by salivary gland epithelium, dendritic cells, osteoclasts, and peritoneal macrophages. It can form homodimers or heterodimers with FGF basic, and it signals through CXCR3 or CXCR5. CXCL13 induces the migration of naïve B cells and a subset of memory T cells to lymphoid tissue. It also promotes B1 cell migration into the omentum and peritoneum. In the fetus, CXCL13 attracts CD4+ CD3- IL-7 R alpha+ hematopoietic cells to sites of future Peyer’s patch development.

Product Specifications for Simple Plex Control for Human CXCL13/BLC/BCA-1

Species	Human, Non-human Primate
Applications	Control, Simple Plex Automated Immunoassay
Source	N/A

Preparation & Storage

Shipping Conditions

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Background: CXCL13/BLC/BCA-1

Entrez Gene IDs

10563 (Human); 55985 (Mouse)

Alternate Names

ANGIE2, Angie, B cell-attracting chemokine 1, B lymphocyte chemoattractant, B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1), B-lymphocyte chemoattractant, BCA-1, BCA-1CXC chemokine BLC, BCA1, BCA1B-cell chemoattractant, BLC, BLCSmall-inducible cytokine B13, BLR1L, C-X-C motif chemokine 13, CXCL13, SCYB13, SCYB13B-cell-attracting chemokine 1, chemokine (C-X-C motif) ligand 13, chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant), small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cellchemoattractant)

Product Documents for Simple Plex Control for Human CXCL13/BLC/BCA-1

Product Datasheets

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