Simple Plex Control for Human IL-8/CXCL8 Best Seller

Name: Simple Plex Control for Human IL-8/CXCL8
Brand: ProteinSimple
SKU: 894950

ProteinSimple, part of Bio-Techne | Catalog # 894950

Product Datasheet / COA

Control for use with Human and Non-Human Primate IL-8/CXCL8 Simple Plex Cartridge Kit

Summary for Simple Plex Control for Human IL-8/CXCL8

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human and NHP IL-8/CXCL8 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.

Product Specifications for Simple Plex Control for Human IL-8/CXCL8

Species	Human, Non-human Primate
Applications	Control, Simple Plex Automated Immunoassay
Source	N/A

Preparation & Storage

Shipping Conditions

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Background: IL-8/CXCL8

Item	Value
Long Name	Interleukin 8
Entrez Gene IDs	3576 (Human); 396880 (Porcine); 403850 (Canine); 493836 (Feline)
Alternate Names	3-10C, AMCF-I, C-X-C motif chemokine 8, CXCL8, CXCL8SCYB8, Emoctakin, GCP-1TSG-1, GCP1, IL-8, IL8, K60, LAI, LECT, LUCT, LYNAP, MDNCF, MDNCFb-ENAP, MONAP, MONAPGCP1, NAF, NAP-1NAP1, NAP1, NCF, Neutrophil-activating protein 1, Protein 3-10C, T cell chemotactic factor, T-cell chemotactic factor, TCF, TSG1, interleukin 8, member 8

Product Documents for Simple Plex Control for Human IL-8/CXCL8

Product Datasheets

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