INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human LBP concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.
Lipopolysaccharide-binding protein (LBP), a 58kDa glycoprotein synthesized in hepatocytes, belongs to a family of lipid-binding proteins that includes bactericidal/permeability increasing protein (BPI), phospholipid ester transfer protein (PLTP), and cholesterol ester transfer protein (CETP). LBP binds to the lipidA portion of lipopolysaccharide (LPS) to facilitate the process of LPS monomerization, catalyzes the binding of LPS monomers to CD14, and promotes LPS-induced immune response.
Product Specifications for Simple Plex Control for Human LBP
Species
Human
Applications
Control, Simple Plex Automated Immunoassay
Source
N/A
Preparation & Storage
Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt. • Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended. • Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: LBP
Item
Value
Long Name
Lipopolysaccharide-binding Protein
Entrez Gene IDs
3929 (Human); 16803 (Mouse)
Alternate Names
LBP, LPS-binding protein, MGC22233, lipopolysaccharide binding protein, lipopolysaccharide-binding protein
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