Simple Plex Human Cystatin C Cartridge

Name: Simple Plex Human Cystatin C Cartridge
Brand: ProteinSimple
SKU: SPCKB-PS-007569

ProteinSimple, part of Bio-Techne | Catalog # SPCKB-PS-007569

Simple Plex Human Cystatin C assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

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Key Product Details

Simple Plex Human Cystatin C Cartridge Summary:

Simple Plex assay for the detection of human Cystatin C in cell culture supernatant (CCS), serum, plasma (EDTA/Heparin), saliva, urine, and cerebrospinal fluid (CSF)

*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay’s minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.

View Full Technical Details for Simple Plex Human Cystatin C Cartridge

Technical Data
Citations

Product Specifications for Simple Plex Human Cystatin C Cartridge

Assay Type	Automated sandwich ELISA
Format	Microfluidic cartridge containing three Glass Nano Reactors (GNR)
Specificity	Natural and recombinant human Cystatin C
Cross-reactivity	< 0.5% cross-reactivity observed with available related molecules. Cross-species reactivity observed with 1 or more species tested.
Interference	No significant interference observed with available related molecules.

Linearity

Samples containing and/or spiked with high concentrations of human Cystatin C were serially diluted with Sample Diluent to produce samples within the dynamic range of the assay.

Scientific Data Examples for Simple Plex Human Cystatin C Cartridge

	Human Cystatin C Ella Assay Standard Curve

Preparation and Storage

Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Cystatin C

Cystatin C is a secreted cysteine protease inhibitor that inhibits Cathepsins B, H, K, L, and S. Cystatin C serum concentration correlates closely to the glomerular filtration rate (GFR); elevated levels are associated with coronary artery and cardiovascular disease risk. Dysregulation of Cystatin C can modulate tumor growth and metastasis. In humans, the L68Q variant forms dimers and oligomers more easily than wild type protein and is the cause for hereditary Cystatin C amyloid angiopathy.

Item	Value
Entrez Gene IDs	1471 (Human); 13010 (Mouse); 25307 (Rat)
Alternate Names	ARMD11, CST3, Cystatin C, Gamma-trace, MGC117328, Neuroendocrine basic polypeptide, Post-gamma-globulin, bA218C14.4 (cystatin C), cystatin 3, cystatin C (amyloid angiopathy and cerebral hemorrhage), cystatin-3, cystatin-C

Compatible Instruments

Ella - Automated Immunoassay Platform | ProteinSimple

Ella from ProteinSimple, a Bio-Techne brand. Get single or multiplex immunoassay results in less than 90 minutes that are consistent and highly reproducible.

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Product Documents for Simple Plex Human Cystatin C Cartridge

Product Datasheets

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Protocols & Manuals

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