1A-116

Biological Activity for 1A-116

Technical Data for 1A-116

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 1A-116

References for 1A-116

References are publications that support the biological activity of the product.

• Cardama et al. Preclinical development of novel Rac1-GEF signaling inhibitors using a rational design approach in highly aggressive breast cancer cell lines. Anticancer Agents Med.Chem., 2014;14:840 PMID: 24066799
• Gonzalez et al. Pharmacological inhibition of Rac1-PAK1 axis restores tamoxifen sensitivity in human resistant breast cancer cells. Cell Signal., 2017;30:154 PMID: 27939839
• Cabrera et al. Pharmacological Rac1 inhibitors with selective apoptotic activity in human acute leukemic cell lines. Oncotarget., 2017;8:98509 PMID: 29228706