2-Furoyl-LIGRLO-amide

Name: 2-Furoyl-LIGRLO-amide
Brand: Tocris Bioscience
SKU: 3015

Tocris Bioscience, part of Bio-Techne | Catalog # 3015

(1)

Citations (2)

COA / SDS

Potent and selective PAR2 agonist

Key Product Details

Purity:	≥95%
Molecular Weight:	777.96 kDa

View Full Technical Details for 2-Furoyl-LIGRLO-amide

Technical Data
Citations / Reviews (1)

Biological Activity for 2-Furoyl-LIGRLO-amide

2-Furoyl-LIGRLO-amide is a potent and selective PAR₂ receptor agonist (pD₂ = 7.0). Causes a dose-dependent relaxation of murine femoral arteries.

Technical Data for 2-Furoyl-LIGRLO-amide

M. Wt	777.96 kDa
Formula	C₃₆H₆₃N₁₁O₈
Storage	Store at -20°C
Purity	≥95%
CAS Number	729589-58-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 2-Furoyl-LIGRLO-amide

Solubility

Soluble Soluble to 1 mg/ml in water

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References for 2-Furoyl-LIGRLO-amide

References are publications that support the biological activity of the product.

McGuire et al. 2-Furoyl-LIGRLO-amide: a potent and selective proteinase-activated receptor 2 agonist. J.Pharmacol.Exp.Ther., 2004;309:1124 PMID: 14976230
Alshurafa et al. A protease activated receptor-2 (PAR-2) activating peptide, tc-LIGRLO-NH₂, induces protease release from mast cells: role in TNF degradation. BMC Pharmacol., 2004;4:12 PMID: 15265236
Olianas et al. Proteinase-activated receptors 1 and 2 in rat olfactory system: layer-specific regulation of multiple signaling pathways in the main olfactory bulb and induction of neurite retraction in olfactory sensory neurons. Neuroscience, 2007;146:1289 PMID: 17434682