2B-(SP)

Name: 2B-(SP)
Brand: Tocris Bioscience
SKU: 1802

Tocris Bioscience, part of Bio-Techne | Catalog # 1802

COA / SDS

Selective GSK-3 phosphopeptide substrate

Discontinued Product

1802 has been discontinued. View all Enzyme Substrates products.

Key Product Details

Description:	Selective GSK-3 phosphopeptide substrate
Molecular Weight:	1835.88

View Full Technical Details for 2B-(SP)

Technical Data
Citations

Biological Activity for 2B-(SP)

2B-(SP) is a selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3); derived from the phosphorylation site of the translation factor eIF2B.

Technical Data for 2B-(SP)

M. Wt	1835.88
Formula	C₇₁H₁₂₃N₂₆O₂₉P
Single Letter Sequence	RRAAEELDSRAGSPQL (Modifications: Ser-13 = pSer)
Storage	Desiccate at -20°C
CAS Number	186901-17-7
PubChem ID	90488714
InChi Key	LBVCQYQHTKHZRY-APZQELAWSA-N
Smiles	[H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](COP(O)(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for 2B-(SP)

References are publications that support the biological activity of the product.

Williams Phosphorylated seryl and threonyl, but not tyrosyl, residues are efficient specificity determinants for GSK-3β and Shaggy. FEBS Lett. 1999 PMID: 10217415
Welsh Peptide substrates suitable for assaying glycogen synthase kinase-3 in crude cell extracts. Anal.Biochem. 1997 PMID: 9025901

2B-(SP)

Tocris Bioscience, part of Bio-Techne | Catalog # 1802

Key Product Details

Biological Activity for 2B-(SP)

Technical Data for 2B-(SP)

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for 2B-(SP)

Product Documents for 2B-(SP)

COA

Certificate of Analysis

SDS

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