3',3'-cGAMP sodium salt

Name: 3',3'-cGAMP sodium salt
Brand: Tocris Bioscience
SKU: 5946

Tocris Bioscience, part of Bio-Techne | Catalog # 5946

Citations (1)

COA / SDS

STING agonist

Discontinued Product

5946 has been discontinued. View all STING Agonists products.

Key Product Details

Description:	STING agonist
Chemical Name:	3',3'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt
Purity:	≥98% (HPLC)
Molecular Weight:	718.37

View Full Technical Details for 3',3'-cGAMP sodium salt

Technical Data
Citations

Biological Activity for 3',3'-cGAMP sodium salt

3',3'-cGAMP sodium salt is a STING agonist. Reduces B cell proliferation and induces apoptosis of malignant B cells in vitro. Suppresses 5TGM1 multiple myeloma xenograft growth in immunodeficient mice, and induces leukemic regression in Eμ-TCL1 mice.

This product is sold in units of 359μg, equivalent to 0.5μmol.

Technical Data for 3',3'-cGAMP sodium salt

M. Wt	718.37
Formula	C₂₀H₂₂N₁₀Na₂O₁₃P₂
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	2407516-83-8
PubChem ID	121513907
InChi Key	MFPHQIYDBUVTRL-DQNSRKNCSA-L
Smiles	[H][C@@]12COP(O[C@@]3([H])[C@@H](O)[C@@H](O[C@]3([H])COP(O[C@@]1([H])[C@@H](O)[C@@H](O2)N4C=NC5=C4N=C(NC5=O)N)(O[Na])=O)N6C=NC7=C(N)N=CN=C67)(O[Na])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for 3',3'-cGAMP sodium salt

References are publications that support the biological activity of the product.

Tang Agonist-mediated activation of STING induces apoptosis in malignant B cells. Cancer Res. 2016 PMID: 26951929

3',3'-cGAMP sodium salt

Tocris Bioscience, part of Bio-Techne | Catalog # 5946

Key Product Details

Biological Activity for 3',3'-cGAMP sodium salt

Technical Data for 3',3'-cGAMP sodium salt

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for 3',3'-cGAMP sodium salt

Product Documents for 3',3'-cGAMP sodium salt

COA

Certificate of Analysis

SDS

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