4-Thiouridine

Name: 4-Thiouridine
Brand: Tocris Bioscience
SKU: 7005

Tocris Bioscience, part of Bio-Techne | Catalog # 7005

Citations (9)

COA / SDS

Photoreactive uridine analog for RNA sequencing

Key Product Details

Chemical Name:	4-Thiouridine
Purity:	≥98%

View Full Technical Details for 4-Thiouridine

Technical Data
Citations

Biological Activity for 4-Thiouridine

4-Thiouridine is a photoreactive uridine analog for RNA sequencing (RNA seq) and thiol(SH)-linked alkylation for the metabolic sequencing of RNA (SLAM seq). Used as a crosslinker to identify RNA binding proteins. Is incorporated into newly transcribed RNA and can be used to track RNA from synthesis to degradation.

Technical Data for 4-Thiouridine

Formula	C₉H₁₂N₂O₅S
Storage	Store at -20°C
Purity	≥98%
CAS Number	13957-31-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 4-Thiouridine

Solubility

Soluble Soluble to 100 mM in water and to 100 mM in DMSO

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for 4-Thiouridine

References are publications that support the biological activity of the product.

Schofield et al. TimeLapse-seq: adding a temporal dimension to RNA sequencing through nucleoside recoding. Nat.Methods, 2018;15:221 PMID: 29355846
Garibaldi et al. Isolation of newly transcribed RNA using the metabolic label 4-thiouridine. Methods Mol.Biol., 2017;1648:169 PMID: 28766297
Herzog et al. Thiol-linked alkylation of RNA to assess expression dynamics. Nat.Methods, 2017;14:1198 PMID: 28945705

4-Thiouridine

Tocris Bioscience, part of Bio-Techne | Catalog # 7005

Key Product Details

Biological Activity for 4-Thiouridine

Technical Data for 4-Thiouridine

Solubility for 4-Thiouridine

Dilution Calculator

Reconstitution Calculator

References for 4-Thiouridine

Product Documents for 4-Thiouridine

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

保持关注