5-Carboxamidotryptamine maleate

Name: 5-Carboxamidotryptamine maleate
Brand: Tocris Bioscience
SKU: 0458

Tocris Bioscience, part of Bio-Techne | Catalog # 0458

Citations (26)

COA / SDS

5-HT1 agonist; also has high affinity for 5-ht5a and 5-HT7

Key Product Details

Description:	5-HT₁ agonist; also has high affinity for 5-ht_5a and 5-HT₇
Alternative Names:	AH-21467,5-CT
Purity:	≥99% (HPLC)
Molecular Weight:	319.32

View Full Technical Details for 5-Carboxamidotryptamine maleate

Technical Data
Citations

Biological Activity for 5-Carboxamidotryptamine maleate

5-Carboxamidotryptamine maleate is a 5-HT₁ agonist with high affinity at 5-HT_1A, 5-HT_1B, 5-HT_1D, 5-ht₅ and 5-HT₇ receptors.

Technical Data for 5-Carboxamidotryptamine maleate

M. Wt	319.32
Formula	C₁₁H₁₃N₃O.C₄H₄O₄
Storage	Store at +4°C
Purity	≥99% (HPLC)
CAS Number	74885-72-6
PubChem ID	11709509
InChi Key	PZQZSWAOVAMBQM-BTJKTKAUSA-N
Smiles	OC(=O)\C=C/C(O)=O.NCCC1=CNC2=CC=C(C=C12)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 5-Carboxamidotryptamine maleate

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	31.93	100

Preparing Stock Solutions for 5-Carboxamidotryptamine maleate

The following data is based on the product molecular weight 319.32.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.13 mL	15.66 mL	31.32 mL
5 mM	0.63 mL	3.13 mL	6.26 mL
10 mM	0.31 mL	1.57 mL	3.13 mL
50 mM	0.06 mL	0.31 mL	0.63 mL

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References for 5-Carboxamidotryptamine maleate

References are publications that support the biological activity of the product.

Wood Antagonist activity of meta-chlorophenylpiperazine and partial agonist activity of 8-OH-DPAT at the 5-HT₇ receptor. Eur.J.Pharmacol. 2000 PMID: 10822046
Nowak [³H]-5-carboxamidotryptamine labels 5HT_1D binding sites in bovine substantia nigra. Br.J.Pharmacol. 1993 PMID: 8401931
Zifa and Fillion 5-Hydroxytryptamine receptors. Pharmacol.Rev. 1992 PMID: 1359584
Beer An investigation of the 5-HT_1D receptor binding affinity of 5-hydroxytryptamine, 5-carboxyamidotryptamine and sumatr. in the central nervous system of seven species. Eur.J.Pharmacol. 1992 PMID: 1325915