6-Bnz-cAMP sodium salt

Name: 6-Bnz-cAMP sodium salt
Brand: Tocris Bioscience
SKU: 5255

Tocris Bioscience, part of Bio-Techne | Catalog # 5255

Citations (15)

COA / SDS

Cell permeable cAMP analog

Key Product Details

Description:	Cell permeable cAMP analog
Chemical Name:	N-Benzoyladenosine cyclic 3',5'-(hydrogen phosphate) monosodium salt
Purity:	≥98% (HPLC)
Molecular Weight:	455.29

View Full Technical Details for 6-Bnz-cAMP sodium salt

Technical Data
Citations

Biological Activity for 6-Bnz-cAMP sodium salt

6-Bnz-cAMP sodium salt is a cell permeable cAMP analog; selectively activates cAMP-dependent PKA but not Epac signaling pathways. Acts synergistically with 8-CPT-2Me-cAMP (Cat. No. 1645) to inhibit vascular smooth muscle cell proliferation.

Technical Data for 6-Bnz-cAMP sodium salt

M. Wt	455.29
Formula	C₁₇H₁₅N₅NaO₇P
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	1135306-29-4
PubChem ID	23672707
InChi Key	SPYGSKQRPXISIB-FKVBDRBCSA-M
Smiles	[H][C@@]([C@@](O[C@@H](N3C=NC4=C3N=CN=C4NC(C5=CC=CC=C5)=O)[C@@H]2O)([H])CO1)2OP1(O[Na])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 6-Bnz-cAMP sodium salt

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	45.53	100

Preparing Stock Solutions for 6-Bnz-cAMP sodium salt

The following data is based on the product molecular weight 455.29.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.20 mL	10.98 mL	21.96 mL
5 mM	0.44 mL	2.20 mL	4.39 mL
10 mM	0.22 mL	1.10 mL	2.20 mL
50 mM	0.04 mL	0.22 mL	0.44 mL

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References for 6-Bnz-cAMP sodium salt

References are publications that support the biological activity of the product.

Hewer PKA and Epac synergistically inhibit smooth muscle cell proliferation. J.Mol.Cell Cardiol. 2011 PMID: 20971121