AACOCF₃

Name: AACOCF 3
Brand: Tocris Bioscience
SKU: 1462
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 1462

(1)

Citations (24)

COA / SDS

Phospholipase A2 inhibitor

Key Product Details

Description:	Phospholipase A₂ inhibitor
Alternative Names:	Arachidonyl trifluoromethyl ketone
Chemical Name:	1,1,1-Trifluoro-6Z,9Z,12Z,15Z-heneicosateraen-2-one
Molecular Weight:	356.47

View Full Technical Details for AACOCF₃

Technical Data
Citations / Reviews (1)

Biological Activity for AACOCF₃

AACOCF₃ is a inhibitor of cytosolic (85 kDa) phospholipase A₂. Also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro.

Technical Data for AACOCF₃

M. Wt	356.47
Formula	C₂₁H₃₁F₃O
Storage	Store at -20°C
CAS Number	149301-79-1
PubChem ID	5280436
InChi Key	PLWROONZUDKYKG-DOFZRALJSA-N
Smiles	O=C(C(F)(F)F)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for AACOCF₃

Solubility

Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 5mg/ml)

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References for AACOCF₃

References are publications that support the biological activity of the product.

Rastogi and McHowat Inhibition of calcium-independent phospholipase A₂ prevents inflammatory mediator production in pulmonary microvascular endothelium. Respir.Physiol.Neurobiol. 2009 PMID: 19059366
Riendeau Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A₂, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. J.Biol.Chem. 1994 PMID: 8195210
Koutek Inhibitors of arachidonoyl ethanolamide hydrolysis. J.Biol.Chem. 1994 PMID: 8083191

AACOCF₃

Tocris Bioscience, part of Bio-Techne | Catalog # 1462

Key Product Details

Biological Activity for AACOCF₃

Technical Data for AACOCF₃

Solubility for AACOCF₃

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for AACOCF₃

Product Documents for AACOCF₃

COA

Certificate of Analysis

SDS

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AACOCF3

Tocris Bioscience, part of Bio-Techne | Catalog # 1462

Key Product Details

Biological Activity for AACOCF3

Technical Data for AACOCF3

Solubility for AACOCF3

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for AACOCF3

Product Documents for AACOCF3

COA

Certificate of Analysis

SDS

AACOCF₃

Biological Activity for AACOCF₃

Technical Data for AACOCF₃

Solubility for AACOCF₃

References for AACOCF₃

Product Documents for AACOCF₃